Why Weight Loss Feels Harder in Perimenopause

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Perimenopause is the transition period leading up to menopause, often starting in a woman’s 40s and lasting several years. During this time, estrogen and progesterone levels fluctuate, which can create changes in weight, mood, energy, and sleep.

mid section weight gain during perimenopause

For many women, perimenopause means:

  • Increased belly fat due to shifting hormones

  • Slower metabolism that makes it harder to burn calories

  • More cravings and hunger caused by hormonal imbalances

  • Low energy and sleep disruptions that reduce motivation

Even women who had no trouble managing their weight before may find themselves frustrated during this stage of life.



How GLP-1 Medications Help

GLP-1 receptor agonists, such as semaglutide (Wegovy) and tirzepatide (Mounjaro/Zepbound), can make a real difference for women in perimenopause.

Here’s how they help:

  • Appetite regulation: GLP-1s slow digestion and signal fullness, making it easier to control cravings and portions.

  • Improved insulin sensitivity: Many women experience blood sugar fluctuations during perimenopause; GLP-1s help regulate these.

  • Steadier energy levels: By preventing energy crashes from overeating or sugar spikes, GLP-1s help women feel more balanced.

Support for sustainable weight loss: Instead of extreme dieting, GLP-1s create a foundation for gradual, lasting results.

When combined with lifestyle support like better sleep habits, strength training, and balanced nutrition, GLP-1s can help women feel more like themselves again.


woman staying active with the help of GLP1 medication and support

Tips for Women in Perimenopause Using GLP-1s

If you’re considering or starting GLP-1 therapy during perimenopause, here are practical tips:

  • Prioritize protein: Helps preserve muscle mass and supports metabolism.

  • Move regularly: Resistance training is especially important for bone and muscle health.

  • Focus on fiber and hydration: Improves digestion and satiety.

  • Track your sleep: Poor sleep can worsen weight gain and mood swings.

Work closely with your provider: Every woman’s experience is unique—your plan should be too.


Why Healthy Resolutions LLC

At Healthy Resolutions LLC, we understand the challenges women face during perimenopause. We provide:

  • Telehealth visits that fit into busy lives

  • Personalized weight loss programs using GLP-1s safely and effectively

  • Support across CT, MA, and NY with a team that understands midlife health challenges

Your journey through perimenopause doesn’t have to mean struggling with your health. With the right tools and support, you can regain balance, energy, and confidence.


If you’re in perimenopause and struggling with weight changes, cravings, or low energy, you don’t have to figure it out alone. Schedule a telehealth consultation with Healthy Resolutions LLC today to explore whether GLP-1 medications could be the solution that helps you thrive.

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